Synthetic Inhibitors of Hyaluronidase. II. New Polycondensed Diphenylmethane and Triphenylmethane Derivatives.
نویسندگان
چکیده
منابع مشابه
Investigation of aminomethyl indole derivatives as hyaluronidase inhibitors.
Hyaluronidase inhibitors are of potential therapeutic value for the treatment of a variety of diseases, such as cancer, arthrosis, or bacterial infections. Potent and selective hyaluronidase inhibitors are not known so far, and current approaches to the development of hyaluronidase inhibitors are limited. Elevated levels of hyaluronan (HA) are connected with most malignant tumours. Therefore, t...
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The possible role of hyaluronidase in the pathogenesis of rheumatic diseases was first suggested some ten years ago (Wallenfels, 1941; Hahn, 1944), since which time the subject has received a fair amount of attention. Certain observations in the literature suggest some interrelationship between the pathological changes of the mesenchymal tissue and an imbalance of the hyaluronidase-hyaluronic -...
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ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1953
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.07-0806